Glucosamine is an amino sugar the body uses to build cartilage – the tough connective tissue that protects the bones in our joints. There are several forms including glucosamine sulfate and glucosamine hydrochloride. Supplementing glucosamine sulfate helps reduce some symptoms of mild osteoarthritis, while glucosamine hydrochloride supports connective tissue, ligament, tendon, and joint cartilage health as well as mobility.